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Microfluidics has been touted as a tool to manipulate fluids at the micro- and nano-liter scales and has shown considerable promise for biology and chemical research. Its unique feature of precisely handling liquids for a chemical or biological assay has made them attractive to replace traditional experiment approaches. This technology can be applied to cell culture and analysis, enzymatic assays, and clinical diagnostics with the advantages of decreased sample volume, parallelization, and ease of downstream integration.